| 2025 | Untold: The Fall of FavreMovie | Self - Host, Anderson 360° (archive footage) | 58 |
| 2024 | What's Next? The Future with Bill GatesSeries | Self (archive footage) | 57 |
| 2024 | The Choice 2024: Harris vs. TrumpMovie | Self (archive footage) | 57 |
| 2022 | Black Panther: Wakanda ForeverMovie | Anderson Cooper | 55 |
| 2022 | Generation GapSeries | Self | 55 |
| 2021 | Madame X Presents: Madame Xtra Q&AMovie | Self | 54 |
| 2021 | A Choice of Weapons: Inspired by Gordon ParksMovie | Self | 54 |
| 2020 | In Delusion: Trump and the American CatastropheMovie | Self (archive footage) | 53 |
| 2020 | The Choice 2020: Trump vs. BidenMovie | Self (archive footage) | 53 |
| 2020 | Visible: Out on TelevisionSeries | Self | 53 |
| 2020 | The New York Times PresentsSeries | Self (archive footage) | 53 |
| 2020 | Coronavirus, ExplainedSeries | Self (archive footage) | 53 |
| 2018 | ExplainedSeries | Self (archive footage) | 51 |
| 2017 | The Words That Built AmericaMovie | Self - Reader: Declaration of Independence | 50 |
| 2016 | Batman v Superman: Dawn of JusticeMovie | Anderson Cooper | 49 |
| 2016 | WIRED's Autocomplete InterviewsSeries | Self - Guest | 49 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 48 |
| 2014 | Last Week Tonight with John OliverSeries | Self | 47 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 47 |
| 2014 | Drew Peterson: UntouchableMovie | Self (archive footage) | 47 |
| 2014 | At This Hour with Kate BolduanSeries | Self | 47 |
| 2012 | Finding Your RootsSeries | Self | 45 |
| 2011 | The ChewSeries | Self | 44 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 42 |
| 2007 | CNN HeroesSeries | Self - Host | 40 |
| 2007 | Ghosts of Abu GhraibMovie | Self (archive footage) | 40 |
| 2006 | When the Levees Broke: A Requiem in Four ActsSeries | Self | 39 |
| 2006 | The Howard Stern InterviewSeries | Self | 39 |
| 2005 | The Colbert ReportSeries | Self | 38 |
| 2005 | Iron Chef AmericaSeries | Self | 38 |
| 2005 | The Situation Room with Wolf BlitzerSeries | — | 38 |
| 2005 | Kathy Griffin: My Life on the D-ListSeries | Self | 38 |
| 2003 | Anderson Cooper 360°Series | Self - Host | 36 |
| 2003 | Real Time with Bill MaherSeries | Self | 36 |
| 2003 | Jimmy Kimmel Live!Series | Self - Guest | 36 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 36 |
| 1997 | The ViewSeries | Self | 30 |
| 1996 | The Daily ShowSeries | Self | 29 |
| 1992 | The Tonight Show with Jay LenoSeries | Self | 25 |
| 1989 | The SimpsonsSeries | Anderson Cooper (voice) | 22 |
| 1988 | LIVE with Kelly and MarkSeries | Self - Guest | 21 |
| 1985 | Larry King LiveSeries | Self | 18 |
| 1984 | Jeopardy!Series | Self - Host | 17 |
| 1981 | Entertainment TonightSeries | Self | 14 |
| 1975 | Saturday Night LiveSeries | Self - Cameo (uncredited) | 8 |
| 1969 | Sesame StreetSeries | — | 2 |
| 1968 | 60 MinutesSeries | Self | 1 |
