Filmography81 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | Toy Story 5Movie | Bo Peep (voice) | 74 |
| 2024 | Georgie & Mandy's First MarriageSeries | Meemaw | 72 |
| 2024 | Ghostbusters: Frozen EmpireMovie | Janine Melnitz | 72 |
| 2022 | The Jennifer Hudson ShowSeries | Self | 70 |
| 2022 | SherriSeries | Self - Guest | 70 |
| 2021 | Arlo the Alligator BoyMovie | Edmée (voice) | 69 |
| 2021 | I Heart ArloSeries | Edmee (voice) | 69 |
| 2021 | Ghostbusters: AfterlifeMovie | Janine Melnitz | 69 |
| 2020 | Reunited ApartSeries | Self | 68 |
| 2020 | Stars in the HouseSeries | Self | 68 |
| 2020 | Lamp LifeMovie | Bo Peep (voice) | 68 |
| 2019 | Toy Story 4Movie | Bo Peep (voice) | 67 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 67 |
| 2019 | The Movies That Made UsSeries | Janine Melnitz (archive footage) | 67 |
| 2018 | Izzy Gets the F*ck Across TownMovie | Mary | 66 |
| 2017 | Young SheldonSeries | Connie Tucker | 65 |
| 2016 | GhostbustersMovie | Desk Clerk | 64 |
| 2015 | Chicago MedSeries | Helen | 63 |
| 2015 | Toy Story at 20: To Infinity and BeyondMovie | Self | 63 |
| 2014 | NCIS: New OrleansSeries | Olivia Brody | 62 |
| 2013 | Instant MomSeries | Roberta Montgomery | 61 |
| 2013 | The FostersSeries | Sharon Elkin | 61 |
| 2012 | ScandalSeries | Louise Baker | 60 |
| 2012 | Animal PracticeSeries | Virginia Coleman | 60 |
| 2012 | GCBSeries | Gigi Stopper | 60 |
| 2012 | Randy Cunningham: 9th Grade NinjaSeries | Tawny Zingwald (voice) | 60 |
| 2011 | FiveMovie | Helen | 59 |
| 2010 | The TalkSeries | Self | 58 |
| 2010 | Fish HooksSeries | Nurse Fishington (voice) | 58 |
| 2010 | Don't You Forget About MeMovie | Self | 58 |
| 2009 | Royal PainsSeries | Mrs. Sacani | 57 |
| 2006 | Ugly BettySeries | Linda | 54 |
| 2006 | Men in TreesSeries | Mary Alice O'Donnell | 54 |
| 2005 | Grey's AnatomySeries | Joyce Bosco | 53 |
| 2005 | Close to HomeSeries | Dr. Marla Dodds | 53 |
| 2004 | Boston LegalSeries | Joy Espenson | 52 |
| 2004 | Elvis Has Left the BuildingMovie | Shirl | 52 |
| 2003 | Two and a Half MenSeries | Lenore | 51 |
| 2003 | Joan of ArcadiaSeries | Lieutenant Lucy Preston | 51 |
| 2003 | Defending Our Kids: The Julie Posey StoryMovie | Julie Posey | 51 |
| 1999 | Law & Order: Special Victims UnitSeries | Sophie Devere | 47 |
| 1999 | Toy Story 2Movie | Bo Peep (voice) | 47 |
| 1998 | Any Day NowSeries | Mary Elizabeth Sims | 46 |
| 1997 | The ViewSeries | Self | 45 |
| 1997 | Over the TopSeries | Hadley Martin | 45 |
| 1996 | Dangerous MindsSeries | Louanne Johnson | 44 |
| 1996 | The Rosie O'Donnell ShowSeries | Self | 44 |
| 1996 | The Story Behind 'Toy Story'Movie | Self | 44 |
| 1995 | Toy StoryMovie | Bo Peep (voice) | 43 |
| 1995 | The Making of Toy StoryMovie | Narrator | 43 |
| 1993 | MeggamorphosisMovie | The Egg | 41 |
| 1992 | Love & WarSeries | Dana Palladino | 40 |
| 1990 | TexasvilleMovie | Karla Jackson | 38 |
| 1989 | Who's Harry Crumb?Movie | Helen Downing | 37 |
| 1989 | Ghostbusters IIMovie | Janine Melnitz | 37 |
| 1989 | Hanna-Barbera's 50thMovie | Self - Host | 37 |
| 1988 | She's Having a BabyMovie | Annie Potts (uncredited) | 36 |
| 1988 | Pass the AmmoMovie | Darla | 36 |
| 1987 | The Man Who Fell to EarthMovie | Louise | 35 |
| 1986 | Designing WomenSeries | Mary Jo Shively | 34 |
| 1986 | Jumpin' Jack FlashMovie | Liz Carlson | 34 |
| 1986 | Pretty in PinkMovie | Iona | 34 |
| 1985 | Amazing StoriesSeries | Mrs. Bev Binford (voice) | 33 |
| 1985 | The Twilight ZoneSeries | (segment "Wordplay") | 33 |
| 1985 | The Comedy FactorySeries | Annie | 33 |
| 1985 | Lime StreetSeries | — | 33 |
| 1984 | GhostbustersMovie | Janine Melnitz | 32 |
| 1984 | Crimes of PassionMovie | Amy Grady | 32 |
| 1984 | Why Me?Movie | Daria | 32 |
| 1984 | It Came Upon the Midnight ClearMovie | Cindy Mills | 32 |
| 1982 | Remington SteeleSeries | Annie Carpenter | 30 |
| 1982 | Something So RightMovie | Sunday | 30 |
| 1981 | HeartachesMovie | Bonnie Howard | 29 |
| 1980 | The Scarlett O'Hara WarMovie | Betty (uncredited) | 28 |
| 1980 | Goodtime GirlsSeries | Edith Bedelmeyer | 28 |
| 1980 | Magnum, P.I.Series | Tracy Spencer | 28 |
| 1979 | Black Market BabyMovie | Linda Cleary | 27 |
| 1979 | Flatbed Annie & Sweetie Pie: Lady TruckersMovie | Flatbed Annie | 27 |
| 1978 | Corvette SummerMovie | Vanessa | 26 |
| 1978 | King of the GypsiesMovie | Persa | 26 |
| 1975 | People's Choice AwardsSeries | Self - Host | 23 |