Filmography121 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2025 | Cheech & Chong's Last MovieMovie | Self | 79 |
| 2025 | Radiator Springs Racers | Disneyland ResortMovie | Ramone (voice) | 79 |
| 2024 | LEGO Pixar: BrickToonsSeries | Ramone (voice) | 78 |
| 2024 | The Long GameMovie | Pollo | 78 |
| 2023 | The Muppets MayhemSeries | Cheech Marin | 77 |
| 2022 | Generation GapSeries | Self - Celebrity Guest | 76 |
| 2022 | The Legend of Vox MachinaSeries | Trinket (voice) | 76 |
| 2022 | Cypress Hill: Insane in the BrainMovie | Self | 76 |
| 2022 | Angry NeighborsMovie | Hector (voice) | 76 |
| 2021 | Quentin Tarantino: From a Movie Buff to a Hollywood LegendMovie | Self (archive footage) | 75 |
| 2021 | Home EconomicsSeries | Roberto | 75 |
| 2021 | Maya and the ThreeSeries | Hura/Can (voice) | 75 |
| 2021 | Classic Albums: Frank Zappa & The Mothers Of Invention - Freak Out!Movie | Self | 75 |
| 2020 | The War with GrandpaMovie | Danny | 74 |
| 2020 | AGFA Mystery Mixtape #4: Follow Your Own StarMovie | Self | 74 |
| 2020 | The AGFA Mystery Mixtape VaultMovie | (archive footage) | 74 |
| 2019 | Inmate #1: The Rise of Danny TrejoMovie | Self | 73 |
| 2018 | Lodge 49Series | — | 72 |
| 2017 | SteveSeries | Self | 71 |
| 2017 | CocoMovie | Corrections Officer (voice) | 71 |
| 2016 | Dark HarvestMovie | Ricardo | 70 |
| 2016 | Good FortuneMovie | Self | 70 |
| 2015 | The Latin Explosion: A New AmericaMovie | Self | 69 |
| 2014 | Jane the VirginSeries | Edward | 68 |
| 2014 | The Radiator Springs 500½Movie | Ramone (voice) | 68 |
| 2014 | Butch DEVO And The Sundance GigMovie | Self - Master of Ceremonies | 68 |
| 2013 | SpinningMovie | Ramone (voice) | 67 |
| 2012 | Anger ManagementSeries | Hector | 66 |
| 2012 | Inside ComedySeries | Self | 66 |
| 2012 | Gotham Comedy LiveSeries | Self - Host | 66 |
| 2011 | Cars 2Movie | Ramone (voice) | 65 |
| 2011 | Bubble GuppiesSeries | Fogzilla (voice) | 65 |
| 2011 | Hoodwinked Too! Hood VS. EvilMovie | Mad Hog (voice) | 65 |
| 2010 | MacheteMovie | Padre Cortez | 64 |
| 2010 | Cheech & Chong's Hey Watch ThisMovie | Self | 64 |
| 2009 | The Perfect GameMovie | Padre Estaban | 63 |
| 2009 | Waking Sleeping BeautyMovie | Tito (voice) (archive footage) | 63 |
| 2009 | Race to Witch MountainMovie | Eddie | 63 |
| 2008 | Beverly Hills ChihuahuaMovie | Manuel (voice) | 62 |
| 2008 | Free RadioSeries | Cheech Marin | 62 |
| 2007 | Planet TerrorMovie | Priest | 61 |
| 2007 | GrindhouseMovie | Padre (segment "Planet Terror") | 61 |
| 2007 | Uncle PMovie | Juan | 61 |
| 2007 | Bloodsucking CinemaMovie | Self | 61 |
| 2006 | PsychSeries | Deacon Jones | 60 |
| 2006 | CarsMovie | Ramone (voice) | 60 |
| 2006 | Mater and the GhostlightMovie | Ramone (voice) | 60 |
| 2006 | Cheech Marin & Friends: Live from South BeachMovie | Self - Host | 60 |
| 2005 | Grey's AnatomySeries | Otis Sharon | 59 |
| 2005 | American Dad!Series | Horatio (voice) | 59 |
| 2005 | Mind of MenciaSeries | — | 59 |
| 2005 | UnderclassmanMovie | Captain Victor Delgado | 59 |
| 2005 | The Princes of MalibuSeries | Self | 59 |
| 2004 | LostSeries | David Reyes | 58 |
| 2004 | Christmas with the KranksMovie | Officer Salino | 58 |
| 2003 | Once Upon a Time in MexicoMovie | Belini | 57 |
| 2003 | Real Time with Bill MaherSeries | Self | 57 |
| 2003 | Spy Kids 3-D: Game OverMovie | Felix Gumm | 57 |
| 2003 | The Brothers Garcia: Mysteries of the MayaMovie | Don Cortez | 57 |
| 2003 | Good Boy!Movie | The Greater Dane's Henchman (voice) | 57 |
| 2003 | Masked and AnonymousMovie | Prospero | 57 |
| 2003 | Mike's Super Short ShowSeries | — | 57 |
| 2003 | This So-Called DisasterMovie | Esteban | 57 |
| 2002 | George LopezSeries | Lalo | 56 |
| 2002 | Spy Kids 2: The Island of Lost DreamsMovie | Felix Gumm | 56 |
| 2001 | Laughing Out Loud: America's Funniest ComediansMovie | Self (archive footage) | 55 |
| 2001 | Spy KidsMovie | Felix Gumm | 55 |
| 2000 | Picking Up the PiecesMovie | Mayor Machado | 54 |
| 1999 | Judging AmySeries | Ignacio Messina | 53 |
| 1999 | GrassMovie | Self (archive footage) | 53 |
| 1999 | The Nuttiest NutcrackerMovie | Mac (Voice) | 53 |
| 1998 | Hollywood SquaresSeries | Self - Panelist | 52 |
| 1997 | South ParkSeries | Carlos Ramirez (voice) | 51 |
| 1997 | The ViewSeries | Self - Guest | 51 |
| 1997 | Classic AlbumsSeries | Self | 51 |
| 1997 | Behind the MusicSeries | Self | 51 |
| 1996 | Nash BridgesSeries | Joe Dominguez | 50 |
| 1996 | From Dusk Till DawnMovie | Border Guard / Chet Pussy / Carlos | 50 |
| 1996 | E! True Hollywood StorySeries | — | 50 |
| 1996 | Tin CupMovie | Romeo Posar | 50 |
| 1995 | Happily Ever After: Fairy Tales for Every ChildSeries | Alberto (voice) | 49 |
| 1995 | DesperadoMovie | Short Bartender | 49 |
| 1995 | The CourtyardMovie | Angel Steiner | 49 |
| 1995 | Charlie's Ghost StoryMovie | Coronado | 49 |
| 1994 | The Lion KingMovie | Banzai (voice) | 48 |
| 1994 | A Million to JuanMovie | Shell Shock | 48 |
| 1993 | RawSeries | Self | 47 |
| 1993 | Sesame Street's 25th Birthday: A Musical CelebrationMovie | Self (segment "New Way to Walk") | 47 |
| 1992 | The Golden PalaceSeries | Chuy Castillos | 46 |
| 1992 | FernGully: The Last RainforestMovie | Stump (voice) | 46 |
| 1990 | Dream OnSeries | Waiter | 44 |
| 1990 | Mother Goose Rock 'n' RhymeMovie | Carnival Barker | 44 |
| 1990 | Far Out ManMovie | Cheech Marin | 44 |
| 1989 | The SimpsonsSeries | Cheech Marin (voice) | 43 |
| 1989 | Tales from the CryptSeries | Dr. Beneloy | 43 |
| 1989 | Ghostbusters IIMovie | Dock Supervisor | 43 |
| 1989 | Rude AwakeningMovie | Jesús Monteya | 43 |
| 1989 | Troop Beverly HillsMovie | Cheech Marin | 43 |
| 1988 | Mickey's 60th BirthdayMovie | Disneyland Janitor | 42 |
| 1988 | Oliver & CompanyMovie | Tito (voice) | 42 |
| 1987 | Married... with ChildrenSeries | Buck the Dog (voice) | 41 |
| 1987 | Fatal BeautyMovie | Bartender | 41 |
| 1987 | Born in East L.A.Movie | Rudy | 41 |
| 1985 | After HoursMovie | Neil | 39 |
| 1985 | Get Out of My RoomMovie | Cheech | 39 |
| 1985 | Echo ParkMovie | Syd | 39 |
| 1984 | Cannonball Run IIMovie | Tire Store Employee (uncredited) | 38 |
| 1984 | Jeopardy!Series | Self | 38 |
| 1983 | YellowbeardMovie | El Segundo | 37 |
| 1983 | Group MadnessMovie | Self | 37 |
| 1983 | Still SmokinMovie | Cheech | 37 |
| 1983 | Return EngagementMovie | Self | 37 |
| 1983 | Playboy Video Magazine, Volume 3Movie | — | 37 |
| 1982 | Things Are Tough All OverMovie | Cheech / Mr. Slyman | 36 |
| 1982 | It Came from HollywoodMovie | Self | 36 |
| 1981 | Nice DreamsMovie | Cheech | 35 |
| 1980 | Cheech & Chong's Next MovieMovie | Cheech / Dwayne "Red" Mendoza | 34 |
| 1978 | Up in SmokeMovie | Pedro | 32 |
| 1975 | People's Choice AwardsSeries | Self - Host | 29 |
| 1971 | Rollin' On The RiverSeries | — | 25 |
| 0 | Naya: Legend of the Golden DolphinMovie | Dude (voice) | — |