Filmography72 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | Marc by SofiaMovie | Self | 52 |
| 2025 | After the HuntMovie | Dr. Kim Sayers | 51 |
| 2024 | Monsters: The Lyle and Erik Menendez StorySeries | Mary Louise 'Kitty' Menendez | 50 |
| 2024 | As Time Goes ByMovie | — | 50 |
| 2023 | Poker FaceSeries | Ruby Ruin | 49 |
| 2022 | Bones and AllMovie | Janelle | 48 |
| 2022 | Hermanos Menendez: Mal juzgados?Series | Mary Louise 'Kitty' Menendez | 48 |
| 2020 | We Are Who We AreSeries | Sarah Wilson | 46 |
| 2020 | DisclosureMovie | Lana Tisdel (archive footage) | 46 |
| 2019 | Russian DollSeries | Lenora Vulvokov | 45 |
| 2019 | The ActSeries | Mel | 45 |
| 2018 | Lean on PeteMovie | Bonnie | 44 |
| 2018 | LizzieMovie | Lizzie Borden | 44 |
| 2017 | FEUDSeries | C. Z. Guest | 43 |
| 2017 | The SnowmanMovie | Sylvia Ottersen / Ane Pedersen | 43 |
| 2017 | The DinnerMovie | Barbara Lohman | 43 |
| 2017 | Comrade DetectiveSeries | Sonya Baciu (voice) | 43 |
| 2017 | Beatriz at DinnerMovie | Shannon | 43 |
| 2017 | Ballad of a Righteous MerchantMovie | Self | 43 |
| 2016 | Love & FriendshipMovie | Alicia Johnson | 42 |
| 2016 | AntibirthMovie | Sadie | 42 |
| 2015 | Black Dog, Red DogMovie | Ali | 41 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self - Guest | 40 |
| 2014 | Variety Studio: Actors on ActorsSeries | Self | 40 |
| 2014 | Late Night with Seth MeyersSeries | Self | 40 |
| 2014 | Electric SlideMovie | Charlotte | 40 |
| 2014 | Little AccidentsMovie | Kendra Briggs | 40 |
| 2013 | The FrameSeries | Jennie | 39 |
| 2012 | The Mindy ProjectSeries | Christina | 38 |
| 2012 | Finding Your RootsSeries | Self | 38 |
| 2011 | American Horror StorySeries | Alex Lowe | 37 |
| 2011 | PortlandiaSeries | Alexandra | 37 |
| 2011 | Fight for Your Right RevisitedMovie | Girl in Limo | 37 |
| 2010 | Mr. NiceMovie | Judy Marks | 36 |
| 2010 | Beautiful DarlingMovie | Candy Darling (voice) | 36 |
| 2010 | Barry MundayMovie | Jennifer Farley | 36 |
| 2009 | RuPaul's Drag RaceSeries | Self - Guest Judge | 35 |
| 2009 | The Killing RoomMovie | Ms. Reilly | 35 |
| 2008 | LyingMovie | Megan | 34 |
| 2007 | ZodiacMovie | Melanie | 33 |
| 2007 | Cannes: All AccessMovie | Self | 33 |
| 2006 | Big LoveSeries | Nicolette Grant | 32 |
| 2006 | Mrs. HarrisMovie | Lynne Tryforos | 32 |
| 2005 | Jiminy Glick in LalawoodMovie | Chloë Sevigny (uncredited) | 31 |
| 2005 | Broken FlowersMovie | Carmen's Assistant | 31 |
| 2005 | Beastie Boys Solid Gold HitsMovie | Self | 31 |
| 2005 | 3 NeedlesMovie | Clara the Novice | 31 |
| 2004 | Dogville ConfessionsMovie | Self | 30 |
| 2003 | Shattered GlassMovie | Caitlin Avey | 29 |
| 2003 | Death of a DynastyMovie | Sexy Woman #1 | 29 |
| 2003 | DogvilleMovie | Liz Henson | 29 |
| 2003 | The Brown BunnyMovie | Daisy Lemon | 29 |
| 2003 | Making of 'Demonlover'Movie | Self | 29 |
| 2002 | DemonloverMovie | Elise Lipsky | 28 |
| 2002 | Ten Minutes Older: The TrumpetMovie | (segment "Int. Trailer Night") | 28 |
| 2000 | American PsychoMovie | Jean | 26 |
| 2000 | If These Walls Could Talk 2Movie | Amy | 26 |
| 2000 | Beastie Boys: Video AnthologyMovie | Self | 26 |
| 1999 | Law & Order: Special Victims UnitSeries | Christine Hartwell | 25 |
| 1999 | Boys Don't CryMovie | Lana Tisdel | 25 |
| 1999 | A Map of the WorldMovie | Carole Mackessy | 25 |
| 1999 | Julien Donkey-BoyMovie | Pearl | 25 |
| 1999 | The Confession of Julien Donkey-BoyMovie | Self | 25 |
| 1998 | Will & GraceSeries | Monet | 24 |
| 1998 | PalmettoMovie | Odette | 24 |
| 1997 | The ViewSeries | Self | 23 |
| 1997 | GummoMovie | Dot | 23 |
| 1995 | X-GirlMovie | — | 21 |
| 1953 | The OscarsSeries | Self | — |
| 1949 | The Emmy AwardsSeries | Self | — |
| 0 | The Lonely WomanMovie | — | — |
| 0 | The Trial of Louise WoodwardSeries | Elaine Whitfield Sharp | — |