Filmography47 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2024 | ElsbethSeries | Reverend Mother Constance Mary Cabot | 76 |
| 2022 | My Father's DragonMovie | Iris the Rhinoceros (voice) | 74 |
| 2021 | Only Murders in the BuildingSeries | Lorraine | 73 |
| 2021 | I Care a LotMovie | Jennifer Peterson | 73 |
| 2021 | Mayor of KingstownSeries | Miriam McLusky | 73 |
| 2018 | The MuleMovie | Mary | 70 |
| 2015 | Life in PiecesSeries | Joan Short | 67 |
| 2015 | SistersMovie | Deana Ellis | 67 |
| 2013 | The BlacklistSeries | Ruth Kipling | 65 |
| 2012 | The Odd Life of Timothy GreenMovie | Ms. Bernice Crudstaff | 64 |
| 2011 | Woody Allen: A DocumentaryMovie | Self | 63 |
| 2011 | The Big YearMovie | Brenda Harris | 63 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 61 |
| 2009 | RageMovie | Miss Roth | 61 |
| 2008 | In TreatmentSeries | Dr. Gina Toll | 60 |
| 2008 | Synecdoche, New YorkMovie | Ellen Bascomb / Millicent Weems | 60 |
| 2007 | Dan in Real LifeMovie | Nana | 59 |
| 2006 | A Guide to Recognizing Your SaintsMovie | Dito's Mother | 58 |
| 2005 | RobotsMovie | Mrs. Copperbottom (voice) | 57 |
| 2004 | The Blackwater LightshipMovie | Lily | 56 |
| 2001 | I Am SamMovie | Annie Cassell | 53 |
| 2001 | Law & Order: Criminal IntentSeries | Nora Lewin | 53 |
| 2000 | The 10th KingdomSeries | Evil Queen | 52 |
| 1999 | Law & Order: Special Victims UnitSeries | Interim D.A. Nora Lewin | 51 |
| 1998 | Practical MagicMovie | Aunt Jet | 50 |
| 1998 | The Horse WhispererMovie | Diane Booker | 50 |
| 1996 | The AssociateMovie | Sally Dugan | 48 |
| 1994 | Cops & RobbersonsMovie | Helen Robberson | 46 |
| 1994 | The ScoutMovie | Doctor H. Aaron | 46 |
| 1991 | Little Man TateMovie | Jane Grierson | 43 |
| 1990 | Law & OrderSeries | Nora Lewin | 42 |
| 1990 | Edward ScissorhandsMovie | Peg | 42 |
| 1990 | The Making of Edward ScissorhandsMovie | Self | 42 |
| 1989 | ParenthoodMovie | Helen Buckman Lampkin Bowman | 41 |
| 1989 | CookieMovie | Lenore | 41 |
| 1988 | Bright Lights, Big CityMovie | Mother | 40 |
| 1987 | Radio DaysMovie | Aunt Bea | 39 |
| 1987 | The Lost BoysMovie | Lucy Emerson | 39 |
| 1986 | Hannah and Her SistersMovie | Holly | 38 |
| 1985 | The Purple Rose of CairoMovie | Emma | 37 |
| 1984 | FootlooseMovie | Vi Moore | 36 |
| 1984 | Falling in LoveMovie | Isabelle | 36 |
| 1983 | Independence DayMovie | Nancy Morgan | 35 |
| 1980 | It's My TurnMovie | Gail | 32 |
| 1971 | Great PerformancesSeries | Elizabeth Gertrude Stern | 23 |
| 1953 | The OscarsSeries | Self | 5 |
| 1951 | Hallmark Hall of FameSeries | Lily | 3 |