Filmography35 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | GOATMovie | Rosette - Shadows Bull (voice) | 44 |
| 2025 | Court of GoldSeries | Self | 43 |
| 2023 | Gabrielle Union: My Journey to 50Series | Self | 41 |
| 2022 | The Redeem TeamMovie | Self - USA 2004 | 40 |
| 2022 | The King of South BeachMovie | Self | 40 |
| 2022 | ShaqSeries | Self | 40 |
| 2022 | They Call Me MagicSeries | Self | 40 |
| 2021 | Adele One Night OnlyMovie | Self | 39 |
| 2020 | FearlessMovie | Private Wade (voice) | 38 |
| 2020 | D. Wade: Life UnexpectedMovie | Self | 38 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 37 |
| 2019 | Desus & MeroSeries | Self - Illustrious Guest | 37 |
| 2018 | Basketball: A Love StorySeries | Self (archive footage) | 36 |
| 2018 | Shut Up and DribbleSeries | Self - NBA Player | 36 |
| 2015 | The Late Show with Stephen ColbertSeries | Self | 33 |
| 2015 | Taylor Swift: The 1989 World Tour - LiveMovie | Self - Special Guest | 33 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self | 32 |
| 2014 | Late Night with Seth MeyersSeries | Self | 32 |
| 2014 | Curt Flood: The Athlete Who Made LeBron James PossibleMovie | Self (Archive Footage) | 32 |
| 2014 | IversonMovie | — | 32 |
| 2012 | What to Expect When You're ExpectingMovie | Dwyane Wade | 30 |
| 2012 | 2012 NBA Champions: Miami HeatMovie | Himself | 30 |
| 2011 | Austin & AllySeries | Self | 29 |
| 2010 | Just WrightMovie | Dwayne Wade | 28 |
| 2009 | The Cleveland ShowSeries | — | 27 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 27 |
| 2005 | Deal or No DealSeries | Self | 23 |
| 2005 | It's the ShoesSeries | Self | 23 |
| 2003 | Jimmy Kimmel Live!Series | Self | 21 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 21 |
| 1996 | The Daily ShowSeries | Self | 14 |
| 1992 | The Tonight Show with Jay LenoSeries | Self - Guest | 10 |
| 1988 | LIVE with Kelly and MarkSeries | Self | 6 |
| 1975 | Saturday Night LiveSeries | Self - Cameo (uncredited) | — |
| 1975 | People's Choice AwardsSeries | Self - Presenter | — |