Filmography48 titles
Importing filmography…
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2025 | Thelma & Louise: Born to LiveMovie | Self | 69 |
| 2022 | SherriSeries | Self- Guest | 66 |
| 2019 | This Changes EverythingMovie | Self | 63 |
| 2018 | Be Natural: The Untold Story of Alice Guy-BlachéMovie | Self | 62 |
| 2017 | GLOWSeries | Sandy Devereaux St. Clair | 61 |
| 2017 | The Fabulous Allan CarrMovie | Self (archive) | 61 |
| 2017 | Don't Talk to IreneMovie | Geena Davis | 61 |
| 2016 | The ExorcistSeries | Angela Rance | 60 |
| 2015 | The Late Late Show with James CordenSeries | Self - Guest | 59 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 58 |
| 2013 | In a World...Movie | Katherine Huling | 57 |
| 2012 | ComaSeries | Dr. Agnetta Lindquist | 56 |
| 2007 | The Graham Norton ShowSeries | Self | 51 |
| 2005 | Commander in ChiefSeries | Mackenzie Allen | 49 |
| 2005 | Grey's AnatomySeries | Nicole Herman | 49 |
| 2005 | The Reichen ShowSeries | Self - Guest | 49 |
| 2005 | Stuart Little 3: Call of the WildMovie | Mrs. Little (voice) | 49 |
| 2003 | Jimmy Kimmel Live!Series | Self | 47 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 47 |
| 2003 | Thelma & Louise: The Last JourneyMovie | Self | 47 |
| 2002 | Stuart Little 2Movie | Mrs. Little | 46 |
| 1998 | Will & GraceSeries | Janet Adler | 42 |
| 1997 | The ViewSeries | Self | 41 |
| 1996 | The Rosie O'Donnell ShowSeries | Self - Guest | 40 |
| 1996 | The Long Kiss GoodnightMovie | Samantha Caine / Charly Baltimore | 40 |
| 1995 | Cutthroat IslandMovie | Morgan Adams | 39 |
| 1994 | Inside the Actors StudioSeries | Self | 38 |
| 1994 | SpeechlessMovie | Julia | 38 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 37 |
| 1993 | Sesame Street's 25th Birthday: A Musical CelebrationMovie | Self (segment "Monster in the Mirror") | 37 |
| 1992 | A League of Their OwnMovie | Dottie Hinson (C) | 36 |
| 1992 | HeroMovie | Gale Gayley | 36 |
| 1991 | Thelma & LouiseMovie | Thelma | 35 |
| 1990 | Quick ChangeMovie | Phyllis Potter | 34 |
| 1990 | The Earth Day SpecialMovie | Kim | 34 |
| 1988 | LIVE with Kelly and MarkSeries | Self - Guest | 32 |
| 1988 | BeetlejuiceMovie | Barbara | 32 |
| 1988 | The Accidental TouristMovie | Muriel Pritchett | 32 |
| 1985 | George Burns Comedy WeekSeries | — | 29 |
| 1985 | Transylvania 6-5000Movie | Odette | 29 |
| 1985 | FletchMovie | Larry | 29 |
| 1984 | RiptideSeries | Dr. Melba Bozinsky | 28 |
| 1982 | Remington SteeleSeries | Sandy Dalrymple | 26 |
| 1982 | Knight RiderSeries | Grace Fallon | 26 |
| 1982 | TootsieMovie | April | 26 |
| 1982 | Family TiesSeries | Karen Nicholson | 26 |
| 1975 | Saturday Night LiveSeries | Self - Host | 19 |
| 1953 | The OscarsSeries | Self | — |