Filmography103 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2025 | Marty SupremeMovie | Kay Stone | 53 |
| 2025 | Variety & CNN Actors on ActorsSeries | Self | 53 |
| 2025 | Good Hang with Amy PoehlerSeries | Self - Guest | 53 |
| 2022 | The KardashiansSeries | Self | 50 |
| 2021 | American Horror StoriesSeries | Daphne (Voice) | 49 |
| 2020 | The Drew Barrymore ShowSeries | Self | 48 |
| 2019 | Avengers: EndgameMovie | Pepper Potts | 47 |
| 2019 | The Chef ShowSeries | Self - Guest | 47 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 47 |
| 2018 | Avengers: Infinity WarMovie | Pepper Potts | 46 |
| 2018 | Red Table TalkSeries | Self | 46 |
| 2017 | Spider-Man: HomecomingMovie | Pepper Potts | 45 |
| 2017 | Carpool Karaoke: The SeriesSeries | Self | 45 |
| 2016 | ChelseaSeries | Self | 44 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 43 |
| 2015 | The Late Late Show with James CordenSeries | Self - Guest | 43 |
| 2015 | Hot OnesSeries | Self - Guest | 43 |
| 2015 | MortdecaiMovie | Johanna Mortdecai | 43 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self | 42 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 42 |
| 2014 | Marvel Studios: Assembling a UniverseMovie | Self | 42 |
| 2013 | Iron Man 3Movie | Pepper Potts | 41 |
| 2012 | The AvengersMovie | Pepper Potts | 40 |
| 2012 | Marvel Studios: Building a Cinematic UniverseMovie | Self | 40 |
| 2011 | ContagionMovie | Beth Emhoff | 39 |
| 2011 | Web TherapySeries | Maya Ganesh | 39 |
| 2011 | Glee: The Concert MovieMovie | Holly Holliday (uncredited) | 39 |
| 2010 | Iron Man 2Movie | Pepper Potts | 38 |
| 2010 | Who Do You Think You Are?Series | Self | 38 |
| 2010 | The Marriage RefSeries | Self - Panelist | 38 |
| 2010 | ConanSeries | Self | 38 |
| 2009 | GleeSeries | Holly Holliday | 37 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 37 |
| 2009 | Late Night with Jimmy FallonSeries | Self - Guest | 37 |
| 2009 | Shark TankSeries | Self - Shark | 37 |
| 2008 | Iron ManMovie | Pepper Potts | 36 |
| 2008 | Valentino: The Last EmperorMovie | Self | 36 |
| 2008 | Two LoversMovie | Michelle Rausch | 36 |
| 2007 | The Graham Norton ShowSeries | Self | 35 |
| 2007 | The Good NightMovie | Dora Epstein | 35 |
| 2006 | El hormigueroSeries | Ella misma | 34 |
| 2006 | Rachael RaySeries | — | 34 |
| 2006 | Love and Other DisastersMovie | Jacks | 34 |
| 2006 | Running with ScissorsMovie | Hope Finch | 34 |
| 2006 | InfamousMovie | Kitty Dean | 34 |
| 2005 | ProofMovie | Catherine Llewellyn | 33 |
| 2005 | The Reichen ShowSeries | Self - Guest | 33 |
| 2004 | Sky Captain and the World of TomorrowMovie | Polly Perkins | 32 |
| 2003 | Jimmy Kimmel Live!Series | Self - Guest | 31 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 31 |
| 2003 | SylviaMovie | Sylvia Plath | 31 |
| 2003 | Late Night with Conan O'Brien: 10th Anniversary SpecialMovie | Self | 31 |
| 2003 | Celebrities UncensoredSeries | Self | 31 |
| 2003 | View from the TopMovie | Donna | 31 |
| 2002 | Austin Powers in GoldmemberMovie | Dixie Normous | 30 |
| 2002 | Searching for Debra WingerMovie | Self | 30 |
| 2002 | American IdolSeries | Self | 30 |
| 2002 | Last Call with Carson DalySeries | Self | 30 |
| 2001 | Shallow HalMovie | Rosemary Shanahan | 29 |
| 2001 | The Royal TenenbaumsMovie | Margot Tenenbaum | 29 |
| 2001 | Good Day LiveSeries | Self | 29 |
| 2001 | Playboy Mansion Parties UncensoredMovie | Self | 29 |
| 2001 | The Anniversary PartyMovie | Skye Davidson | 29 |
| 2000 | Scary MovieMovie | Viola de Lesseps (archival footage) | 28 |
| 2000 | DuetsMovie | Liv | 28 |
| 2000 | InternMovie | Gwyneth Paltrow (uncredited) | 28 |
| 2000 | ClerksSeries | Gwyneth Paltrow (voice) | 28 |
| 1999 | The Talented Mr. RipleyMovie | Marge Sherwood | 27 |
| 1999 | Teen Choice AwardsSeries | Self | 27 |
| 1999 | DogmaMovie | Woman at Airport (uncredited) | 27 |
| 1998 | Shakespeare in LoveMovie | Viola De Lesseps | 26 |
| 1998 | Great ExpectationsMovie | Estella | 26 |
| 1998 | ParkinsonSeries | Self | 26 |
| 1998 | A Perfect MurderMovie | Emily Bradford Taylor | 26 |
| 1998 | Sliding DoorsMovie | Helen Quilley | 26 |
| 1997 | The ViewSeries | Self | 25 |
| 1997 | Hard EightMovie | Clementine | 25 |
| 1997 | Thomas JeffersonSeries | Jefferson's grandaughter (voice) | 25 |
| 1996 | The Daily ShowSeries | Self | 24 |
| 1996 | The Rosie O'Donnell ShowSeries | Self - Guest | 24 |
| 1996 | EmmaMovie | Emma Woodhouse | 24 |
| 1995 | Se7enMovie | Tracy | 23 |
| 1995 | Lo + plusSeries | Self - Guest | 23 |
| 1995 | Moonlight and ValentinoMovie | Lucy Trager | 23 |
| 1995 | Jefferson in ParisMovie | Patsy Jefferson | 23 |
| 1995 | The Actor Awards Presented by SAG-AFTRASeries | Self | 23 |
| 1994 | Inside the Actors StudioSeries | Self | 22 |
| 1994 | Mrs. Parker and the Vicious CircleMovie | Paula Hunt | 22 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 21 |
| 1993 | Flesh and BoneMovie | Ginnie | 21 |
| 1993 | Deadly RelationsMovie | Carol Ann Fagot | 21 |
| 1993 | Late Night with Conan O'BrienSeries | Self - Guest | 21 |
| 1992 | The Tonight Show with Jay LenoSeries | Self | 20 |
| 1992 | Cruel DoubtSeries | Angela Pritchard | 20 |
| 1991 | HookMovie | Young Wendy | 19 |
| 1988 | LIVE with Kelly and MarkSeries | — | 16 |
| 1984 | Goldene KameraSeries | Self | 12 |
| 1981 | Entertainment TonightSeries | Self | 9 |
| 1975 | Saturday Night LiveSeries | Self - Host | 3 |
| 1975 | Good Morning AmericaSeries | Self | 3 |
| 1953 | The OscarsSeries | Self | — |
| 1948 | BambiSeries | Self | — |
| 1944 | Golden Globe AwardsSeries | Self | — |