Filmography82 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | David Attenborough's 100 Years on Planet EarthMovie | Self (archive footage) | 49 |
| 2026 | Other MommyMovie | Mommy / Other Mommy | 49 |
| 2026 | HeartlandMovie | Misty Jones | 49 |
| 2025 | DreamsMovie | Jennifer McCarthy | 48 |
| 2025 | The 99th Annual Macy's Thanksgiving Day ParadeMovie | Self | 48 |
| 2025 | Family Recipe ShowdownSeries | Guest Judge | 48 |
| 2024 | Better Angels: The Gospel According to Tammy FayeSeries | Self | 47 |
| 2023 | Liv Ullmann: A Road Less TravelledSeries | Self | 46 |
| 2022 | The 355Movie | Mason 'Mace' Brown | 45 |
| 2022 | Reframed: Marilyn MonroeSeries | Narrator (voice) | 45 |
| 2022 | The Good NurseMovie | Amy Loughren | 45 |
| 2021 | The Eyes of Tammy FayeMovie | Tammy Faye Bakker | 44 |
| 2021 | Scenes from a MarriageSeries | Mira Phillips | 44 |
| 2019 | Dark PhoenixMovie | Vuk | 42 |
| 2019 | It Chapter TwoMovie | Beverly Marsh | 42 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 42 |
| 2019 | This Changes EverythingMovie | Self | 42 |
| 2019 | The Summers of It - Chapter Two: It EndsMovie | Self | 42 |
| 2018 | Family FeudMovie | Presidents' interviewer | 41 |
| 2018 | Woman Walks AheadMovie | Catherine Weldon | 41 |
| 2018 | Half the PictureMovie | Self (archive footage) | 41 |
| 2017 | Molly's GameMovie | Molly Bloom | 40 |
| 2017 | I Am Jane DoeMovie | Narrator (voice) | 40 |
| 2017 | The Zookeeper's WifeMovie | Antonina Żabińska | 40 |
| 2016 | The Huntsman: Winter's WarMovie | Sara | 39 |
| 2016 | Miss SloaneMovie | Madeline Elizabeth Sloane | 39 |
| 2016 | ChelseaSeries | Self | 39 |
| 2016 | WIRED's Autocomplete InterviewsSeries | Self - Guest | 39 |
| 2015 | The MartianMovie | Melissa Lewis | 38 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 38 |
| 2015 | Crimson PeakMovie | Lady Lucille Sharpe | 38 |
| 2015 | ARES: liveSeries | Melissa Lewis | 38 |
| 2015 | UnityMovie | Narrator (voice) | 38 |
| 2015 | Close Up with The Hollywood ReporterSeries | Self | 38 |
| 2014 | InterstellarMovie | Murph | 37 |
| 2014 | A Most Violent YearMovie | Anna Morales | 37 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self - Guest | 37 |
| 2014 | Variety Studio: Actors on ActorsSeries | Self | 37 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 37 |
| 2014 | Off Camera with Sam JonesSeries | Self | 37 |
| 2014 | The Disappearance of Eleanor Rigby: HerMovie | Eleanor Rigby | 37 |
| 2014 | The Disappearance of Eleanor Rigby: HimMovie | Eleanor Rigby | 37 |
| 2014 | The Disappearance of Eleanor Rigby: ThemMovie | Eleanor Rigby | 37 |
| 2014 | Interstellar: Nolan's OdysseyMovie | Self | 37 |
| 2013 | MamaMovie | Annabel | 36 |
| 2013 | Letters to Jackie: Remembering President KennedyMovie | Self - Letter Reader | 36 |
| 2013 | Seduced and AbandonedMovie | Self | 36 |
| 2013 | Wilde SaloméMovie | Self / Salomé | 36 |
| 2013 | SaloméMovie | Salomé | 36 |
| 2012 | Madagascar 3: Europe's Most WantedMovie | Gia (voice) | 35 |
| 2012 | LawlessMovie | Maggie Beauford | 35 |
| 2011 | The HelpMovie | Celia Foote | 34 |
| 2011 | The Tree of LifeMovie | Mrs. O'Brien | 34 |
| 2011 | CoriolanusMovie | Virgilia | 34 |
| 2011 | Exploring 'The Tree of Life'Movie | Self | 34 |
| 2010 | JoleneMovie | Jolene | 33 |
| 2010 | The DebtMovie | Young Rachel Singer | 33 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 32 |
| 2009 | StolenMovie | Sally Ann | 32 |
| 2008 | Between Two Ferns with Zach GalifianakisSeries | Self | 31 |
| 2007 | The Graham Norton ShowSeries | Self - Guest | 30 |
| 2007 | JourneymanSeries | Tanna Bloom | 30 |
| 2006 | 'Til DeathSeries | Hostess | 29 |
| 2006 | BlackbeardSeries | Charlotte Ormand | 29 |
| 2005 | Close to HomeSeries | Casey Wirth | 28 |
| 2005 | Law & Order: Trial by JurySeries | Sigrun Borg | 28 |
| 2005 | Dark ShadowsMovie | Carolyn Stoddard | 28 |
| 2004 | Veronica MarsSeries | Sarah Williams | 27 |
| 2003 | Jimmy Kimmel Live!Series | Self - Guest | 26 |
| 1997 | The ViewSeries | Self - Guest | 20 |
| 1997 | Leute heuteSeries | Self | 20 |
| 1996 | The Daily ShowSeries | Self - Guest | 19 |
| 1994 | ERSeries | Dahlia Taslitz | 17 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 16 |
| 1989 | Agatha Christie's PoirotSeries | Mary Debenham | 12 |
| 1988 | LIVE with Kelly and MarkSeries | Self - Guest | 11 |
| 1984 | Goldene KameraSeries | Self | 7 |
| 1975 | Saturday Night LiveSeries | Self - Host | — |
| 1953 | The OscarsSeries | Self | — |
| 0 | My Darling CaliforniaMovie | Sharon Normandie | — |
| 0 | Lear RexMovie | Goneril | — |
| 0 | The SavantSeries | The Savant | — |