Filmography76 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | Toy Story 5Movie | Jessie (voice) | 64 |
| 2026 | Toy Story: 30 Years and Beyond - A Special Edition of 20/20Movie | Self | 64 |
| 2019 | Toy Story 4Movie | Jessie (voice) | 57 |
| 2019 | Let It SnowMovie | Tin Foil Woman | 57 |
| 2018 | HomecomingSeries | Francine Bunda | 56 |
| 2018 | Instant FamilyMovie | Mrs. Howard | 56 |
| 2017 | SnatchedMovie | Barb | 55 |
| 2017 | A Series of Unfortunate EventsSeries | Justice Strauss | 55 |
| 2017 | Unicorn StoreMovie | Gladys | 55 |
| 2016 | Popstar: Never Stop Never StoppingMovie | Tilly | 54 |
| 2016 | Richard Linklater: Dream Is DestinyMovie | Self (archive footage) (uncredited) | 54 |
| 2015 | Welcome to MeMovie | Dawn Hurley | 53 |
| 2015 | Freaks of NatureMovie | Peg Parker | 53 |
| 2014 | Toy Story That Time ForgotMovie | Jessie (voice) | 52 |
| 2013 | Toy Story of Terror!Movie | Jessie (Voice) | 51 |
| 2012 | Partysaurus RexMovie | Jessie (voice) | 50 |
| 2012 | The Perks of Being a WallflowerMovie | Dr. Burton | 50 |
| 2011 | ShamelessSeries | Sheila Jackson | 49 |
| 2011 | Hawaiian VacationMovie | Jessie (voice) | 49 |
| 2011 | Small FryMovie | Jessie (voice) | 49 |
| 2011 | Hoodwinked Too! Hood VS. EvilMovie | Verushka the Witch (voice) | 49 |
| 2011 | Arthur ChristmasMovie | Lead Elf (voice) | 49 |
| 2011 | Mars Needs MomsMovie | Mom (voice) | 49 |
| 2010 | Toy Story 3Movie | Jessie (voice) | 48 |
| 2009 | My Sister's KeeperMovie | Judge De Salvo | 47 |
| 2009 | Confessions of a ShopaholicMovie | Jane Bloomwood | 47 |
| 2009 | The Face is FamiliarMovie | — | 47 |
| 2007 | Phineas and FerbSeries | Glenda | 45 |
| 2007 | The Pixar StoryMovie | Jessie (voice) (archive footage) | 45 |
| 2006 | Friends with MoneyMovie | Franny | 44 |
| 2005 | American Dad!Series | Widow Support Group Leader (voice) | 43 |
| 2005 | The OfficeSeries | Erin's Biological Mother | 43 |
| 2005 | Ice PrincessMovie | Joan Carlyle | 43 |
| 2005 | Chicken LittleMovie | Abby Mallard (voice) | 43 |
| 2005 | Saturday Night Live in the '80s: Lost and FoundMovie | Self | 43 |
| 2004 | Raising HelenMovie | Jenny Portman | 42 |
| 2004 | The Last ShotMovie | Fanny Nash (uncredited) | 42 |
| 2003 | Jimmy Kimmel Live!Series | Self - Guest | 41 |
| 2003 | Looney Tunes: Back in ActionMovie | Mother | 41 |
| 2003 | The School of RockMovie | Rosalie Mullins | 41 |
| 2002 | It's a Very Merry Muppet Christmas MovieMovie | Rachel Bitterman | 40 |
| 2001 | What About Joan?Series | Joan Gallagher | 39 |
| 2000 | Where the Heart IsMovie | Ruth Meyers | 38 |
| 2000 | High FidelityMovie | Liz | 38 |
| 1999 | Law & Order: Special Victims UnitSeries | Pam Burton | 37 |
| 1999 | Cradle Will RockMovie | Hazel Huffman | 37 |
| 1999 | Toy Story 2Movie | Jessie (voice) | 37 |
| 1999 | Runaway BrideMovie | Peggy Flemming | 37 |
| 1999 | Hidden Vulnerability: A Look Into the Making of 'Arlington Road'Movie | — | 37 |
| 1997 | The ViewSeries | Self | 35 |
| 1997 | Grosse Pointe BlankMovie | Marcella | 35 |
| 1997 | In & OutMovie | Emily Montgomery | 35 |
| 1997 | A Smile Like YoursMovie | Nancy Tellen | 35 |
| 1996 | Mr. WrongMovie | Inga Gunther | 34 |
| 1995 | Two MuchMovie | Gloria | 33 |
| 1993 | Addams Family ValuesMovie | Debbie Jellinsky | 31 |
| 1992 | The Tonight Show with Jay LenoSeries | — | 30 |
| 1992 | HeroMovie | Evelyn Laplante | 30 |
| 1992 | ToysMovie | Alsatia Zevo | 30 |
| 1991 | PerformanceSeries | Annie | 29 |
| 1991 | The Cabinet of Dr. RamirezMovie | Cathy | 29 |
| 1990 | My Blue HeavenMovie | Hannah Stubbs | 28 |
| 1990 | Men Don't LeaveMovie | Jody | 28 |
| 1989 | Saturday Night Live: 15th AnniversaryMovie | Self | 27 |
| 1989 | Say Anything...Movie | Constance Dobler | 27 |
| 1988 | Working GirlMovie | Cyn | 26 |
| 1988 | Married to the MobMovie | Rose | 26 |
| 1987 | Broadcast NewsMovie | Blair Litton | 25 |
| 1987 | The AllnighterMovie | Gina | 25 |
| 1984 | Grandview, U.S.A.Movie | Mary Maine | 22 |
| 1984 | Sixteen CandlesMovie | Geek Girl #1 | 22 |
| 1983 | ClassMovie | Julia | 21 |
| 1982 | Late Night with David LettermanSeries | Self - Guest | 20 |
| 1975 | Saturday Night LiveSeries | Self - Various Characters | 13 |
| 1971 | Great PerformancesSeries | Anne | 9 |
| 1953 | The OscarsSeries | Jessie (voice) | — |