Filmography95 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | A Prayer for the DyingMovie | Doc | 61 |
| 2025 | Heads or Tails?Movie | Buffalo Bill | 60 |
| 2025 | American ClownMovie | Self | 60 |
| 2023 | Once Upon a StudioMovie | Wreck-It-Ralph (voice) | 58 |
| 2022 | Stars at NoonMovie | American Magazine Editor | 57 |
| 2022 | Winning Time: The Rise of the Lakers DynastySeries | Jerry Buss | 57 |
| 2022 | Minions & More 2Movie | Eddie (voice) | 57 |
| 2021 | Ultra City SmithsSeries | Donovan Smith (voice) | 56 |
| 2021 | Licorice PizzaMovie | Fred Gwynne / Herman Munster (uncredited) | 56 |
| 2018 | Ralph Breaks the InternetMovie | Wreck-It Ralph (voice) | 53 |
| 2018 | Holmes & WatsonMovie | Dr. John Watson | 53 |
| 2018 | The Sisters BrothersMovie | Eli Sisters | 53 |
| 2017 | Kong: Skull IslandMovie | Hank Marlow | 52 |
| 2017 | The Little HoursMovie | Father Tommasso | 52 |
| 2016 | SingMovie | Eddie (voice) | 51 |
| 2016 | WIRED's Autocomplete InterviewsSeries | Self - Guest | 51 |
| 2015 | The Late Show with Stephen ColbertSeries | Self | 50 |
| 2015 | Tale of TalesMovie | King of Longtrellis | 50 |
| 2015 | The Late Late Show with James CordenSeries | Self - Guest | 50 |
| 2015 | Les CowboysMovie | American in Pakistan | 50 |
| 2015 | View from a Blue MoonMovie | Self - Narrator (voice) | 50 |
| 2015 | BagboyMovie | Dr. Steve Brule | 50 |
| 2014 | Guardians of the GalaxyMovie | Corpsman Dey | 49 |
| 2014 | Life After BethMovie | Maury Slocum | 49 |
| 2014 | Tim and Eric's Bedtime StoriesSeries | Jordan | 49 |
| 2014 | Stone QuackersSeries | Officer Barry | 49 |
| 2013 | Anchorman 2: The Legend ContinuesMovie | Ghost of Stonewall Jackson (uncredited) | 48 |
| 2012 | The DictatorMovie | Clayton (uncredited) | 47 |
| 2012 | 8Movie | David Blankenhorn | 47 |
| 2012 | Wreck-It RalphMovie | Ralph (voice) | 47 |
| 2011 | Fight for Your Right RevisitedMovie | Mike D (B-Boys 2) | 46 |
| 2011 | TerriMovie | Mr. Fitzgerald | 46 |
| 2011 | CarnageMovie | Michael Longstreet | 46 |
| 2010 | The Extra ManMovie | Gershon Gruen | 45 |
| 2010 | CyrusMovie | John Kilpatrick | 45 |
| 2009 | 9Movie | #5 (voice) | 44 |
| 2009 | The Jay Leno ShowSeries | Self | 44 |
| 2009 | Cirque du Freak: The Vampire's AssistantMovie | Larten Crepsley | 44 |
| 2008 | Step BrothersMovie | Dale Doback | 43 |
| 2008 | Hollywood Singing and Dancing: A Musical HistoryMovie | Self | 43 |
| 2008 | Prop 8: The MusicalMovie | Prop 8 Leader | 43 |
| 2007 | The Graham Norton ShowSeries | Self | 42 |
| 2007 | Tim and Eric Awesome Show, Great Job!Series | Dr. Steve Brule | 42 |
| 2007 | Walk Hard: The Dewey Cox StoryMovie | Dewey Cox | 42 |
| 2007 | Year of the DogMovie | Al | 42 |
| 2007 | Ricky Jay Plays PokerMovie | Self | 42 |
| 2006 | Tenacious D in The Pick of DestinyMovie | Sasquatch (uncredited) | 41 |
| 2006 | Talladega Nights: The Ballad of Ricky BobbyMovie | Cal Naughton, Jr. | 41 |
| 2005 | Dark WaterMovie | Mr. Murray | 40 |
| 2005 | Beneath the Surface: The Making of 'Dark Water'Movie | Self | 40 |
| 2005 | Kathy Griffin: My Life on the D-ListSeries | Self | 40 |
| 2005 | Are You the Favorite Person of Anybody?Movie | — | 40 |
| 2004 | The AviatorMovie | Noah Dietrich | 39 |
| 2004 | Tom Goes to the MayorSeries | John (voice) | 39 |
| 2004 | CriminalMovie | Richard Gaddis | 39 |
| 2004 | Cracking UpSeries | Steve Evers | 39 |
| 2003 | Anger ManagementMovie | Older Arnie Shankman (uncredited) | 38 |
| 2003 | Jimmy Kimmel Live!Series | Self | 38 |
| 2002 | Gangs of New YorkMovie | Happy Jack | 37 |
| 2002 | The Good GirlMovie | Phil Last | 37 |
| 2002 | ChicagoMovie | Amos Hart | 37 |
| 2001 | The Anniversary PartyMovie | Mac Forsyth | 36 |
| 2000 | Skipped PartsMovie | Cowboy at Pool Table (uncredited) | 35 |
| 2000 | The Perfect StormMovie | Dale "Murp" Murphy | 35 |
| 2000 | That Moment: Magnolia DiaryMovie | Self | 35 |
| 1999 | MagnoliaMovie | Officer Jim Kurring | 34 |
| 1999 | Never Been KissedMovie | Gus Strauss | 34 |
| 1999 | For Love of the GameMovie | Gus Sinski | 34 |
| 1998 | The Thin Red LineMovie | Sgt. Maynard Storm | 33 |
| 1998 | Chicago CabMovie | Steve | 33 |
| 1997 | Boogie NightsMovie | Reed Rothchild | 32 |
| 1997 | The ViewSeries | Self | 32 |
| 1997 | Hard EightMovie | John | 32 |
| 1997 | Tenacious DSeries | Sasquatch | 32 |
| 1997 | Cinema CinemaMovie | Himself | 32 |
| 1996 | The Daily ShowSeries | Self | 31 |
| 1995 | Dolores ClaiborneMovie | Const. Frank Stamshaw | 30 |
| 1995 | GeorgiaMovie | Herman | 30 |
| 1994 | The River WildMovie | Terry | 29 |
| 1993 | What's Eating Gilbert GrapeMovie | Tucker Van Dyke | 28 |
| 1993 | Fallen AngelsSeries | Martin Lonsdale | 28 |
| 1992 | The Tonight Show with Jay LenoSeries | — | 27 |
| 1992 | HoffaMovie | Pete Connelly | 27 |
| 1992 | Out on a LimbMovie | Jim Jr. | 27 |
| 1991 | Shadows and FogMovie | Cop at Police Station | 26 |
| 1990 | Days of ThunderMovie | Buck Bretherton | 25 |
| 1990 | State of GraceMovie | Stevie | 25 |
| 1989 | The SimpsonsSeries | John C. Reilly (voice) | 24 |
| 1989 | Casualties of WarMovie | Private Herbert Hatcher | 24 |
| 1989 | We're No AngelsMovie | Young Monk | 24 |
| 1988 | LIVE with Kelly and MarkSeries | — | 23 |
| 1988 | Above the LawMovie | Thug in Bar (uncredited) | 23 |
| 1981 | Nero WolfeSeries | — | 16 |
| 1975 | Saturday Night LiveSeries | Self - Host | 10 |
| 1953 | The OscarsSeries | Self | — |