| 2026 | KevinSeries | Armando (voice) | 80 |
| 2026 | Vincent Price: What Keeps Us AliveMovie | — | 80 |
| 2026 | Eddie Cochran: Don't Forget MeMovie | Self | 80 |
| 2025 | Velvet Vision: The Story of James Bidgood and the Making of Pink NarcissusMovie | Self | 79 |
| 2025 | Everybody's Live with John MulaneySeries | Self - Writer and Film Director | 79 |
| 2025 | It's Dorothy!Movie | Self | 79 |
| 2024 | Scala!!!Movie | Self | 78 |
| 2024 | As Time Goes ByMovie | — | 78 |
| 2023 | Digman!Series | Magnus (voice) | 77 |
| 2023 | Little Richard: I Am EverythingMovie | Self | 77 |
| 2022 | Charles Band’s Full Moon FreakshowSeries | — | 76 |
| 2022 | Fragments of ParadiseMovie | Self | 76 |
| 2021 | The Velvet UndergroundMovie | Self | 75 |
| 2021 | PrideSeries | Self | 75 |
| 2021 | ChuckySeries | Wendell Wilkins | 75 |
| 2020 | Time Warp Vol. 2: Horror and Sci-FiMovie | Host | 74 |
| 2020 | Helluva BossSeries | Rolando (voice) | 74 |
| 2020 | Time Warp Vol. 1: Midnight MadnessMovie | Host | 74 |
| 2020 | Time Warp: The Greatest Cult Films of All TimeSeries | Self - Host | 74 |
| 2019 | Sniffing Out ‘Polyester’Movie | Self | 73 |
| 2019 | 30/30 Vision: Three Decades of Strand ReleasingMovie | Self | 73 |
| 2019 | Bully. Coward. Victim. The Story of Roy CohnMovie | Self | 73 |
| 2018 | ExplainedSeries | Narrator (voice) | 72 |
| 2017 | FEUDSeries | William Castle | 71 |
| 2017 | Mansfield 66/67Movie | Self | 71 |
| 2016 | Search PartySeries | Sheffield | 70 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 69 |
| 2015 | Tab Hunter ConfidentialMovie | Self | 69 |
| 2015 | Alvin and the Chipmunks: The Road ChipMovie | First Class Passenger | 69 |
| 2015 | Sympathy for the Devil: The True Story of The Process Church of the Final JudgmentMovie | Self | 69 |
| 2014 | ClarenceSeries | Captain Tom (voice) | 68 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 68 |
| 2014 | I Am DivineMovie | Self | 68 |
| 2014 | The Last ImpresarioMovie | Self | 68 |
| 2014 | Suburban GothicMovie | Cornelius | 68 |
| 2013 | The BlacklistSeries | John Waters | 67 |
| 2013 | The Sarnos: A Life in Dirty MoviesMovie | Self | 67 |
| 2013 | RuPaul Drives...Series | Self - Guest | 67 |
| 2012 | Finding Your RootsSeries | Self | 66 |
| 2012 | ExcisionMovie | William | 66 |
| 2012 | MansomeMovie | Self | 66 |
| 2012 | Frankenstein: A Modern MythMovie | Self - Director | 66 |
| 2011 | These Amazing ShadowsMovie | Self | 65 |
| 2011 | Blank CityMovie | Self | 65 |
| 2011 | Mangus!Movie | Jesus Christ | 65 |
| 2010 | Beautiful DarlingMovie | Self | 64 |
| 2010 | Fish HooksSeries | Ezekiel Freshwater / Hair Man (voice) | 64 |
| 2010 | Herschell Gordon Lewis: The Godfather of GoreMovie | — | 64 |
| 2010 | William S. Burroughs: A Man WithinMovie | Self | 64 |
| 2010 | The Simpsons 20th Anniversary Special - In 3D! On Ice!Movie | Self | 64 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 63 |
| 2009 | RuPaul's Drag RaceSeries | Self - Special Guest | 63 |
| 2009 | It Came from KucharMovie | Self | 63 |
| 2008 | The Wild World of Ted V. MikelsMovie | Narrator | 62 |
| 2008 | Starz Inside: In the GutterMovie | Self | 62 |
| 2007 | The Graham Norton ShowSeries | Self - Guest | 61 |
| 2007 | HairsprayMovie | Flasher | 61 |
| 2007 | 'Til Death Do Us PartSeries | — | 61 |
| 2007 | Spine Tingler! The William Castle StoryMovie | Self | 61 |
| 2007 | Here’s Looking at You, BoyMovie | Self | 61 |
| 2007 | 365 Day ProjectMovie | Self | 61 |
| 2007 | Indie SexSeries | Self | 61 |
| 2007 | Jack Smith and the Destruction of AtlantisMovie | Self | 61 |
| 2007 | The Roots of 'Hairspray'Movie | Self | 61 |
| 2007 | Jessica the HippoMovie | Narrator (Voice) | 61 |
| 2006 | I Love the '70s: Volume 2Series | Self | 60 |
| 2006 | Plagues and Pleasures on the Salton SeaMovie | Self - Narrator (voice) | 60 |
| 2006 | Fabulous! The Story of Queer CinemaMovie | Self | 60 |
| 2006 | This Film Is Not Yet RatedMovie | Self - Director of 'A Dirty Shame' | 60 |
| 2006 | (buz'be bur'kle) n. A Study in StyleMovie | Self | 60 |
| 2006 | Footlight Parade: Music for the DecadesMovie | — | 60 |
| 2006 | The Henry Rollins ShowSeries | — | 60 |
| 2006 | Jackass Number TwoMovie | Self | 60 |
| 2006 | That Man: Peter BerlinMovie | Self | 60 |
| 2006 | Treasures Untold: The Making of Disney's 'The Little Mermaid'Movie | Self | 60 |
| 2006 | 42nd Street: From Book to Screen to StageMovie | Self | 60 |
| 2005 | The Colbert ReportSeries | Self - Guest | 59 |
| 2005 | My Name Is EarlSeries | Walter Hamerick | 59 |
| 2005 | Inside Deep ThroatMovie | Self | 59 |
| 2004 | Thinking XXXMovie | Self | 58 |
| 2002 | The CockettesMovie | Self | 56 |
| 2002 | Blood Feast 2: All U Can EatMovie | The Reverend | 56 |
| 2002 | Sylvester: Mighty RealMovie | Self | 56 |
| 2000 | Welcome to HollywoodMovie | John Waters | 54 |
| 1999 | Law & Order: Special Victims UnitSeries | Pornmonger Man | 53 |
| 1999 | Forever HollywoodMovie | Self | 53 |
| 1999 | Yesterday's TomorrowsMovie | Self | 53 |
| 1998 | So Graham NortonSeries | Self - Guest | 52 |
| 1998 | Anarchy TVMovie | — | 52 |
| 1997 | The ViewSeries | Self | 51 |
| 1997 | AnthemMovie | Self | 51 |
| 1996 | The Daily ShowSeries | Self - Guest | 50 |
| 1996 | E! True Hollywood StorySeries | — | 50 |
| 1996 | Ballyhoo: The Hollywood Sideshow!Movie | — | 50 |
| 1995 | God Save the QueensMovie | — | 49 |
| 1994 | Serial MomMovie | Ted Bundy (voice) (uncredited) | 48 |
| 1993 | FrasierSeries | Roger (voice) | 47 |
| 1993 | Homicide: Life on the StreetSeries | R. Vincent Smith | 47 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 47 |
| 1992 | HBO First LookSeries | — | 46 |
| 1991 | Gastronomic GetawayMovie | — | 45 |
| 1990 | The WordSeries | — | 44 |
| 1989 | The SimpsonsSeries | John (voice) | 43 |
| 1989 | Homer and EddieMovie | Robber #1 | 43 |
| 1988 | HairsprayMovie | Dr. Fredrickson | 42 |
| 1988 | The Incredibly Strange Film ShowSeries | Self | 42 |
| 1987 | 21 Jump StreetSeries | Mr. Bean | 41 |
| 1985 | Divine WatersMovie | Self | 39 |
| 1982 | Late Night with David LettermanSeries | Self - Guest | 36 |
| 1975 | Saturday Night LiveSeries | Self - Cameo (uncredited) | 29 |
| 0 | Mary Woronov: Cult QueenMovie | Self | — |
| 0 | BaltigoreMovie | The Broker | — |
| 0 | The Brandon Novak StoryMovie | Self | — |
