Filmography80 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2025 | The TwitsMovie | Mary Muggle-Wump (voice) | 44 |
| 2025 | Fountain of YouthMovie | Charlotte Purdue | 44 |
| 2025 | Ladies & Gentlemen... 50 Years of SNL MusicMovie | Self | 44 |
| 2025 | Good Hang with Amy PoehlerSeries | Self - Guest | 44 |
| 2025 | Garden State - The 20th Anniversary ConcertMovie | Self - Presenter | 44 |
| 2024 | High & Low – John GallianoMovie | Self (archive footage) | 43 |
| 2024 | Lady in the LakeSeries | Maddie Schwartz | 43 |
| 2023 | May DecemberMovie | Elizabeth | 42 |
| 2023 | Off Script with The Hollywood ReporterSeries | Self | 42 |
| 2023 | Beau gesteSeries | Self | 42 |
| 2023 | Angel CitySeries | Self | 42 |
| 2022 | Thor: Love and ThunderMovie | Jane Foster / The Mighty Thor | 41 |
| 2022 | Marvel Studios Assembled: The Making of Thor: Love and ThunderMovie | Self - Jane Foster / The Mighty Thor | 41 |
| 2021 | Marvel Studios LegendsSeries | Jane Foster (archive footage) (uncredited) | 40 |
| 2021 | What If...?Series | Jane Foster (voice) | 40 |
| 2020 | The Drew Barrymore ShowSeries | Self - Guest | 39 |
| 2019 | Avengers: EndgameMovie | Jane Foster | 38 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 38 |
| 2019 | Lucy in the SkyMovie | Lucy Cola | 38 |
| 2019 | The Death & Life of John F. DonovanMovie | Sam Turner | 38 |
| 2019 | This Changes EverythingMovie | Self | 38 |
| 2018 | BlueySeries | Whale Doco Narrator (voice) | 37 |
| 2018 | AnnihilationMovie | Lena | 37 |
| 2018 | Vox LuxMovie | Celeste Montgomery | 37 |
| 2018 | Konbini Vidéo ClubSeries | — | 37 |
| 2017 | Song to SongMovie | Rhonda | 36 |
| 2016 | Angie TribecaSeries | Christina Craft | 35 |
| 2016 | JackieMovie | Jackie Kennedy | 35 |
| 2016 | WIRED's Autocomplete InterviewsSeries | Self - Guest | 35 |
| 2016 | QuotidienSeries | Self - Guest | 35 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 34 |
| 2015 | Jane Got a GunMovie | Jane Hammond | 34 |
| 2015 | Knight of CupsMovie | Elizabeth | 34 |
| 2015 | The Late Late Show with James CordenSeries | Self - Guest | 34 |
| 2015 | Hot OnesSeries | Self | 34 |
| 2015 | The Heyday of the Insensitive BastardsMovie | Laura | 34 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self - Guest | 33 |
| 2014 | Variety Studio: Actors on ActorsSeries | Self | 33 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 33 |
| 2013 | Thor: The Dark WorldMovie | Jane Foster | 32 |
| 2011 | ThorMovie | Jane Foster | 30 |
| 2011 | No Strings AttachedMovie | Emma Kurtzman | 30 |
| 2011 | Your HighnessMovie | Isabel | 30 |
| 2010 | Black SwanMovie | Nina Sayers / The Swan Queen | 29 |
| 2010 | I'm Still HereMovie | Natalie Portman | 29 |
| 2010 | HesherMovie | Nicole | 29 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 28 |
| 2009 | BrothersMovie | Grace Cahill | 28 |
| 2008 | The Other Boleyn GirlMovie | Anne Boleyn | 27 |
| 2008 | New York, I Love YouMovie | Rifka | 27 |
| 2007 | The Graham Norton ShowSeries | Self | 26 |
| 2007 | Mr. Magorium's Wonder EmporiumMovie | Molly Mahoney | 26 |
| 2007 | The Darjeeling LimitedMovie | Jack's Ex-Girlfriend | 26 |
| 2007 | Hotel ChevalierMovie | Jack's Girlfriend | 26 |
| 2007 | My Blueberry NightsMovie | Leslie | 26 |
| 2006 | Paris Je T'aimeMovie | Francine (Faubourg Saint-Denis) | 25 |
| 2006 | V for VendettaMovie | Evey | 25 |
| 2006 | Goya's GhostsMovie | Inés Bilbatúa / Alicia | 25 |
| 2005 | Domino OneMovie | Dominique Bellamy | 24 |
| 2004 | CloserMovie | Alice | 23 |
| 2004 | Garden StateMovie | Sam | 23 |
| 2004 | Sesame Street: Elmo's World: The Street We Live On!Movie | Self (uncredited) | 23 |
| 2003 | Jimmy Kimmel Live!Series | Self - Guest | 22 |
| 2003 | Cold MountainMovie | Sara | 22 |
| 2002 | Star Wars: Episode II - Attack of the ClonesMovie | Padmé Amidala | 21 |
| 2001 | ZoolanderMovie | Natalie Portman | 20 |
| 2000 | Where the Heart IsMovie | Novalee Nation | 19 |
| 1999 | Star Wars: Episode I - The Phantom MenaceMovie | Padmé Amidala | 18 |
| 1999 | Anywhere but HereMovie | Ann August | 18 |
| 1996 | Mars Attacks!Movie | Taffy Dale | 15 |
| 1996 | Everyone Says I Love YouMovie | Laura Dandridge | 15 |
| 1996 | Beautiful GirlsMovie | Marty | 15 |
| 1995 | HeatMovie | Lauren Gustafson | 14 |
| 1994 | Léon: The ProfessionalMovie | Mathilda Lando | 13 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 12 |
| 1989 | The SimpsonsSeries | Darcy (voice) | 8 |
| 1975 | Saturday Night LiveSeries | Self - Host | — |
| 1975 | People's Choice AwardsSeries | Self - Presenter | — |
| 1969 | Sesame StreetSeries | Natalie | — |
| 1967 | OmnibusSeries | — | — |