| 2026 | Untold: The Death & Life of Lamar OdomMovie | Self - Interviewer (archive footage) | 72 |
| 2026 | Michael Jackson: A Life in MusicMovie | Self (archive footage) | 72 |
| 2026 | Jane Elliott Against the WorldMovie | Self (Archive Footage) | 72 |
| 2026 | America Who Are You? A History of the American MindsetSeries | Self (archive footage) | 72 |
| 2025 | Seen & Heard: The History of Black TelevisionSeries | Self | 71 |
| 2025 | An Oprah Winfrey Special: The Menopause RevolutionMovie | Self - Host | 71 |
| 2024 | The Six Triple EightMovie | Mary McLeod Bethune | 70 |
| 2024 | Hollywood BlackSeries | Self (archive footage) | 70 |
| 2024 | The Choice 2024: Harris vs. TrumpMovie | Self (archive footage) | 70 |
| 2024 | Diane von Furstenberg: Woman in ChargeMovie | Self | 70 |
| 2024 | An Oprah Special: The Presleys - Elvis, Lisa Marie and RileyMovie | Self - Host | 70 |
| 2023 | Pretty Baby: Brooke ShieldsSeries | Self (archive footage) | 69 |
| 2023 | 100 Years of Warner Bros.Series | Self | 69 |
| 2023 | The Super ModelsSeries | Self (archive footage) | 69 |
| 2023 | Carol Burnett: 90 Years of Laughter + LoveMovie | Self - Guest | 69 |
| 2023 | The Light We Carry: Michelle Obama and Oprah WinfreyMovie | Self | 69 |
| 2022 | The Jennifer Hudson ShowSeries | Self | 68 |
| 2022 | SherriSeries | Self - Guest | 68 |
| 2022 | Maradona: The FallMovie | Self (archive footage) | 68 |
| 2022 | The Checkup with Dr. David AgusSeries | Self | 68 |
| 2021 | Adele One Night OnlyMovie | Self | 67 |
| 2021 | Oprah Winfrey: Fight for Better LifeMovie | Herself | 67 |
| 2021 | Parkinson at 50Movie | Self (archive footage) | 67 |
| 2021 | TINAMovie | Self | 67 |
| 2021 | Oprah with Meghan and Harry: A CBS Primetime SpecialMovie | Self | 67 |
| 2021 | The Me You Can't SeeSeries | Self | 67 |
| 2021 | The United States vs. Billie Holiday Special: Lee Daniels and Cast Interviewed by Oprah WinfreyMovie | Self | 67 |
| 2021 | Fatal DistractionMovie | Self (archive footage) | 67 |
| 2021 | The Perfect VictimMovie | Self (archive footage) | 67 |
| 2020 | Chadwick Boseman: A Tribute for a KingMovie | Self | 66 |
| 2020 | You Cannot Kill David ArquetteMovie | Self (archive footage) (uncredited) | 66 |
| 2020 | Some Good NewsSeries | Self | 66 |
| 2020 | First LadiesSeries | Self (archive footage) | 66 |
| 2020 | One World: Together at HomeMovie | Self | 66 |
| 2020 | America's Great Divide: From Obama to TrumpSeries | Self (archive footage) | 66 |
| 2020 | The Choice 2020: Trump vs. BidenMovie | Self (archive footage) | 66 |
| 2020 | Visible: Out on TelevisionSeries | Self | 66 |
| 2020 | Dear...Series | Self | 66 |
| 2020 | Oprah Talks COVID-19Series | Self - Host | 66 |
| 2020 | BecomingMovie | Self | 66 |
| 2020 | The Oprah ConversationSeries | Self - Host | 66 |
| 2019 | Tamron HallSeries | Self - Guest | 65 |
| 2019 | Mike Wallace Is HereMovie | Self (archive footage) | 65 |
| 2019 | Toni Morrison: The Pieces I AmMovie | Self | 65 |
| 2019 | Oprah's Book ClubSeries | Self - Host | 65 |
| 2019 | Oprah Winfrey Presents: After NeverlandMovie | Self | 65 |
| 2018 | Patriot Act with Hasan MinhajSeries | Self (archive footage) | 64 |
| 2018 | A Wrinkle in TimeMovie | Mrs. Which | 64 |
| 2018 | QuincyMovie | Self | 64 |
| 2017 | SpielbergMovie | Self | 63 |
| 2017 | Bright Lights: Starring Carrie Fisher and Debbie ReynoldsMovie | Self (archive footage, uncredited) | 63 |
| 2017 | Whitney: Can I Be MeMovie | Self (archive footage) (uncredited) | 63 |
| 2017 | The StarMovie | Deborah (voice) | 63 |
| 2017 | Get Me Roger StoneMovie | Self (archive footage) | 63 |
| 2017 | 13th: A Conversation with Oprah Winfrey & Ava DuVernayMovie | Herself | 63 |
| 2017 | The Immortal Life of Henrietta LacksMovie | Deborah Lacks | 63 |
| 2016 | Before the FloodMovie | Self (archive footage) | 62 |
| 2016 | GreenleafSeries | Mavis McCready | 62 |
| 2016 | Maya Angelou: And Still I RiseMovie | Self | 62 |
| 2016 | National Museum of African American History and Culture Grand Opening CeremonyMovie | Self | 62 |
| 2016 | Enlighten Us: The Rise and Fall of James Arthur RayMovie | Self (archive footage) | 62 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 61 |
| 2015 | The 10 Faces of Michael JacksonMovie | Self (archive footage) | 61 |
| 2015 | Close Up with The Hollywood ReporterSeries | Self | 61 |
| 2014 | Variety Studio: Actors on ActorsSeries | Self | 60 |
| 2014 | SelmaMovie | Annie Lee Cooper | 60 |
| 2014 | LindsaySeries | Self | 60 |
| 2013 | The ButlerMovie | Gloria Gaines | 59 |
| 2013 | Makers: Women Who Make AmericaSeries | Self | 59 |
| 2012 | Steve HarveySeries | Self | 58 |
| 2012 | Jesus Henry ChristMovie | Oprah | 58 |
| 2012 | Oprah: Where Are They Now?Series | Herself - Host | 58 |
| 2011 | Super Soul SundaySeries | Herself - Host | 57 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 55 |
| 2009 | The Princess and the FrogMovie | Eudora (voice) | 55 |
| 2009 | It's ComplicatedMovie | Self (uncredited) | 55 |
| 2008 | Oprah's Big GiveSeries | — | 54 |
| 2007 | Ocean's ThirteenMovie | Oprah Winfrey | 53 |
| 2007 | Keeping Up with the KardashiansSeries | Self | 53 |
| 2007 | Bee MovieMovie | Judge Bumbleton (voice) | 53 |
| 2007 | Everything's CoolMovie | Self (archive footage) | 53 |
| 2006 | 30 RockSeries | Oprah Winfrey | 52 |
| 2006 | Rachael RaySeries | — | 52 |
| 2006 | Web Junk 20Series | — | 52 |
| 2006 | Charlotte's WebMovie | Gussy the Goose (voice) | 52 |
| 2006 | A Special Presentation Oprah and Elie Wiesel at Auschwitz Death CampMovie | Self | 52 |
| 2004 | Drake & JoshSeries | Oprah Winfrey | 50 |
| 2004 | On Air with Ryan SeacrestSeries | Self | 50 |
| 2003 | Anderson Cooper 360°Series | Self | 49 |
| 2003 | Jimmy Kimmel Live!Series | Self | 49 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 49 |
| 2003 | ABC's 50th Anniversary CelebrationMovie | Self | 49 |
| 2003 | Celebrities UncensoredSeries | Self | 49 |
| 2002 | The Cosby Show: A Look BackMovie | Self | 48 |
| 2000 | Life & CookingSeries | Self | 46 |
| 1999 | Tina Turner : Celebrate!Movie | Self | 45 |
| 1998 | The HughleysSeries | Oprah Winfrey | 44 |
| 1998 | ParkinsonSeries | Self | 44 |
| 1998 | BelovedMovie | Sethe | 44 |
| 1997 | The ViewSeries | Self | 43 |
| 1997 | Before Women Had WingsMovie | Zora Williams | 43 |
| 1996 | E! True Hollywood StorySeries | — | 42 |
| 1996 | The Daily ShowSeries | Self | 42 |
| 1994 | All-American GirlSeries | Self | 40 |
| 1994 | EllenSeries | Therapist | 40 |
| 1993 | Late Show with David LettermanSeries | Self - Guest | 39 |
| 1993 | There Are No Children HereMovie | LaJoe Rivers | 39 |
| 1993 | Michael Jackson Talks... to OprahMovie | Self | 39 |
| 1992 | The Tonight Show with Jay LenoSeries | Self | 38 |
| 1992 | LincolnMovie | Elizabeth Keckley (voice) | 38 |
| 1992 | Surviving a Break-UpMovie | Self | 38 |
| 1991 | Home ImprovementSeries | Oprah Winfrey | 37 |
| 1990 | The Fresh Prince of Bel-AirSeries | Oprah Winfrey | 36 |
| 1990 | Brewster PlaceSeries | Mattie Michael | 36 |
| 1990 | Gabriel's FireSeries | — | 36 |
| 1989 | The Women of Brewster PlaceMovie | Mattie Michael | 35 |
| 1989 | The Women of Brewster PlaceSeries | Mattie Michael | 35 |
| 1988 | LIVE with Kelly and MarkSeries | Self - Guest | 34 |
| 1988 | Pee-wee's Playhouse Christmas SpecialMovie | Self | 34 |
| 1987 | DollySeries | Self | 33 |
| 1986 | American MastersSeries | Self | 32 |
| 1986 | Native SonMovie | Mrs. Thomas | 32 |
| 1986 | The Oprah Winfrey ShowSeries | Self - Host | 32 |
| 1985 | The Color PurpleMovie | Sofia | 31 |
| 1982 | Late Night with David LettermanSeries | Self | 28 |
| 1981 | Entertainment TonightSeries | Self | 27 |
| 1979 | CBS News Sunday MorningSeries | Self | 25 |
| 1975 | Saturday Night LiveSeries | Self - Host | 21 |
| 1974 | The Daytime Emmy AwardsSeries | — | 20 |
| 1968 | 60 MinutesSeries | Self | 14 |
| 1959 | The GrammysSeries | Self | 5 |
| 1953 | The OscarsSeries | Self | — |
| 1949 | The Emmy AwardsSeries | Self | — |
