Filmography103 titles
| Year | Title | Character | Age at release |
|---|---|---|---|
| 2026 | Heart of Light: Eleven Songs for FijiMovie | — | 66 |
| 2026 | Queer Edward IIMovie | Self (archive footage) | 66 |
| 2025 | Ballad of a Small PlayerMovie | Cynthia Blithe | 65 |
| 2025 | KarlMovie | Self | 65 |
| 2025 | The Coen Brothers StoryMovie | Self | 65 |
| 2024 | The Room Next DoorMovie | Martha / Michelle | 64 |
| 2024 | ProblemistaMovie | Elizabeth | 64 |
| 2024 | FantasmasSeries | Water (voice) | 64 |
| 2024 | The EndMovie | Mother | 64 |
| 2024 | A Sudden Glimpse to Deeper ThingsMovie | Wilhelmina Barns-Graham (voice) | 64 |
| 2023 | Asteroid CityMovie | Dr. Hickenlooper | 63 |
| 2023 | The KillerMovie | The Expert | 63 |
| 2023 | Personal HistoryMovie | — | 63 |
| 2022 | Three Thousand Years of LongingMovie | Alithea | 62 |
| 2022 | Guillermo del Toro's Pinocchio: Handcarved CinemaMovie | Self | 62 |
| 2021 | Marvel Studios LegendsSeries | The Ancient One (archive footage) (uncredited) | 61 |
| 2021 | What If...?Series | The Ancient One (voice) | 61 |
| 2021 | The French Dispatch of the Liberty, Kansas Evening SunMovie | J.K.L. Berensen | 61 |
| 2021 | The Storms of Jeremy ThomasMovie | Self | 61 |
| 2021 | MemoriaMovie | Jessica Holland | 61 |
| 2020 | Schlingensief – A Voice That Shook the SilenceMovie | Self (archive footage) | 60 |
| 2020 | The Human VoiceMovie | Woman | 60 |
| 2019 | Avengers: EndgameMovie | The Ancient One | 59 |
| 2019 | What We Do in the ShadowsSeries | Tilda | 59 |
| 2019 | The BoysSeries | Ambrosius (voice) | 59 |
| 2019 | Uncut GemsMovie | Anne - Adley's Auction Manager (voice) | 59 |
| 2018 | SuspiriaMovie | Madame Blanc / Dr. Klemperer / Helena Markos | 58 |
| 2018 | Isle of DogsMovie | Oracle (voice) | 58 |
| 2017 | Letters from BaghdadMovie | Gertrude Bell (voice) | 57 |
| 2017 | War MachineMovie | German Politician | 57 |
| 2017 | OkjaMovie | Lucy Mirando / Nancy Mirando | 57 |
| 2017 | async - first lightMovie | — | 57 |
| 2016 | Doctor StrangeMovie | The Ancient One | 56 |
| 2016 | Hail, Caesar!Movie | Thora Thacker / Thessaly Thacker | 56 |
| 2015 | The Late Show with Stephen ColbertSeries | Self | 55 |
| 2015 | TrainwreckMovie | Dianna | 55 |
| 2015 | B-Movie: Lust & Sound in West-Berlin 1979-1989Movie | Self | 55 |
| 2015 | Moonrise Kingdom Extras - Eleven iPhone Videos by Edward Norton.Movie | Self | 55 |
| 2014 | Variety Studio: Actors on ActorsSeries | Self | 54 |
| 2014 | Late Night with Seth MeyersSeries | Self - Guest | 54 |
| 2014 | The Grand Budapest HotelMovie | Madame D. | 54 |
| 2014 | Snowpiercer: Transperceneige, From the Blank Page to the Black ScreenMovie | Self | 54 |
| 2013 | SnowpiercerMovie | Mason | 53 |
| 2013 | David Bowie: Five YearsMovie | Self (archive footage) | 53 |
| 2013 | The Zero TheoremMovie | Dr. Shrink-Rom | 53 |
| 2013 | Love FleshMovie | Self | 53 |
| 2013 | The Stars (Are Out Tonight)Movie | — | 53 |
| 2013 | Rick and MortySeries | The Collective (voice) | 53 |
| 2012 | Moonrise KingdomMovie | Social Services | 52 |
| 2012 | RadiomanMovie | Self | 52 |
| 2012 | Song 1Movie | Self | 52 |
| 2011 | Cinema Is EverywhereMovie | Self | 51 |
| 2010 | I Am LoveMovie | Emma Recchi | 50 |
| 2010 | The Chronicles of Narnia: The Voyage of the Dawn TreaderMovie | White Witch | 50 |
| 2009 | Getting OnSeries | Elke | 49 |
| 2008 | The Curious Case of Benjamin ButtonMovie | Elizabeth Abbott | 48 |
| 2008 | The Chronicles of Narnia: Prince CaspianMovie | White Witch | 48 |
| 2008 | JuliaMovie | Julia | 48 |
| 2008 | The New Ten CommandmentsMovie | Self | 48 |
| 2008 | DerekMovie | Narrator (voice) | 48 |
| 2008 | DC Insiders Run AmuckMovie | Self | 48 |
| 2007 | Michael ClaytonMovie | Karen Crowder | 47 |
| 2007 | Here’s Looking at You, BoyMovie | Self | 47 |
| 2007 | SleepwalkersMovie | Violinist Working As a Copy Clerk | 47 |
| 2007 | Cannes: All AccessMovie | Self (archive footage) | 47 |
| 2007 | Strange CultureMovie | Hope Kurtz | 47 |
| 2006 | Deep WaterMovie | Narrator (voice) | 46 |
| 2005 | ConstantineMovie | Gabriel | 45 |
| 2005 | ThumbsuckerMovie | Audrey Cobb | 45 |
| 2005 | Made in HollywoodSeries | Self | 45 |
| 2005 | Broken FlowersMovie | Penny | 45 |
| 2005 | The SommeMovie | Narrator (voice) | 45 |
| 2005 | The Chronicles of Narnia: The Lion, the Witch and the WardrobeMovie | White Witch | 45 |
| 2003 | The StatementMovie | Annemarie Livi | 43 |
| 2003 | Young AdamMovie | Ella Gault | 43 |
| 2002 | Adaptation.Movie | Valerie Thomas | 42 |
| 2002 | TeknolustMovie | Rosetta / Ruby / Marinne / Olive | 42 |
| 2001 | Vanilla SkyMovie | Rebecca Dearborn | 41 |
| 2001 | The Deep EndMovie | Margaret Hall | 41 |
| 2000 | The BeachMovie | Sal | 40 |
| 1999 | The ProtagonistsMovie | Actress | 39 |
| 1998 | Love Is the Devil: Study for a Portrait of Francis BaconMovie | Muriel Belcher | 38 |
| 1996 | The Daily ShowSeries | Self | 36 |
| 1996 | Female PerversionsMovie | Evelyn Stephens | 36 |
| 1994 | GlitterbugMovie | Self | 34 |
| 1993 | WittgensteinMovie | Lady Ottoline Morrell | 33 |
| 1993 | BlueMovie | (voice) | 33 |
| 1992 | Shakespeare: The Animated TalesSeries | Ophelia (voice) | 32 |
| 1992 | HamletMovie | Ophelia | 32 |
| 1991 | Derek Jarman: A PortraitMovie | Self | 31 |
| 1991 | The Party: Nature MorteMovie | Queenie | 31 |
| 1990 | The GardenMovie | Madonna/Voice Overs | 30 |
| 1990 | Your Cheatin' HeartMovie | — | 30 |
| 1990 | Your Cheatin' HeartSeries | Cissie Crouch | 30 |
| 1989 | War RequiemMovie | The Nurse | 29 |
| 1989 | Volcano SagaMovie | Gudrun | 29 |
| 1987 | AriaMovie | Young Girl | 27 |
| 1987 | Egomania: Island Without HopeMovie | Sally | 27 |
| 1987 | The Last of EnglandMovie | The Maid | 27 |
| 1986 | ScreenPlaySeries | Ella / Max Gerike | 26 |
| 1986 | CaravaggioMovie | Lena | 26 |
| 1986 | Zastrozzi: A RomanceSeries | Julia | 26 |
| 1953 | The OscarsSeries | Self | — |