| 2026 | LorneMovie | Self | 56 |
| 2026 | Saturday Night Live UKSeries | Self - Host | 56 |
| 2025 | SNL50: The Homecoming ConcertMovie | Self | 55 |
| 2025 | Ladies & Gentlemen... 50 Years of SNL MusicMovie | Self | 55 |
| 2025 | Everybody's Live with John MulaneySeries | Self - Actress, Writer, and Comedian | 55 |
| 2025 | Good Hang with Amy PoehlerSeries | Self - Guest | 55 |
| 2025 | Kobe: The Making of a LegendSeries | Self (archive footage) | 55 |
| 2024 | Will & HarperMovie | Self | 54 |
| 2024 | STEVE! (martin) a documentary in 2 piecesSeries | Self - Writer & Actress | 54 |
| 2024 | Mean GirlsMovie | Ms. Norbury | 54 |
| 2023 | A Haunting in VeniceMovie | Ariadne Oliver | 53 |
| 2023 | Carol Burnett: 90 Years of Laughter + LoveMovie | Self - Guest | 53 |
| 2022 | Be My Guest with Ina GartenSeries | Self - Guest | 52 |
| 2022 | Celebrating Betty White: America's Golden GirlMovie | Self | 52 |
| 2021 | Only Murders in the BuildingSeries | Cinda Canning | 51 |
| 2021 | Free GuyMovie | Vacuuming Mom (voice) | 51 |
| 2021 | Girls5evaSeries | Dolly Parton | 51 |
| 2020 | SoulMovie | 22 (voice) | 50 |
| 2020 | 30 Rock: A One-Time SpecialMovie | Liz Lemon | 50 |
| 2020 | Stars in the HouseSeries | Self | 50 |
| 2020 | Mapleworth MurdersSeries | Martha | 50 |
| 2020 | Cup of JoeSeries | Self | 50 |
| 2020 | Feeding America Comedy FestivalMovie | Self | 50 |
| 2019 | Modern LoveSeries | Sarah | 49 |
| 2019 | The Kelly Clarkson ShowSeries | Self | 49 |
| 2018 | My Next Guest Needs No Introduction with David LettermanSeries | Self | 48 |
| 2018 | Busy TonightSeries | Self - Guest | 48 |
| 2018 | Betty White: First Lady of TelevisionMovie | Self | 48 |
| 2017 | Great NewsSeries | Diana St. Tropez | 47 |
| 2015 | Unbreakable Kimmy SchmidtSeries | Andrea Bayden | 45 |
| 2015 | The Late Show with Stephen ColbertSeries | Self - Guest | 45 |
| 2015 | Difficult PeopleSeries | Tina Fey | 45 |
| 2015 | Mary Tyler Moore: A CelebrationMovie | Self | 45 |
| 2015 | SistersMovie | Kate Ellis | 45 |
| 2015 | Thank You, Del: The Story of the Del Close MarathonMovie | Self | 45 |
| 2015 | Live from New York!Movie | Self | 45 |
| 2014 | The Tonight Show Starring Jimmy FallonSeries | Self - Guest | 44 |
| 2014 | Late Night with Seth MeyersSeries | Self | 44 |
| 2014 | This Is Where I Leave YouMovie | Wendy Altman | 44 |
| 2014 | Muppets Most WantedMovie | Nadya | 44 |
| 2014 | Don Rickles: One Night OnlyMovie | Self | 44 |
| 2013 | Anchorman 2: The Legend ContinuesMovie | Jill Janson (uncredited) | 43 |
| 2013 | AdmissionMovie | Portia Nathan | 43 |
| 2012 | RadiomanMovie | Self | 42 |
| 2012 | Finding Your RootsSeries | Self | 42 |
| 2012 | Comedians in Cars Getting CoffeeSeries | Self | 42 |
| 2012 | Inside ComedySeries | Self | 42 |
| 2011 | Bob's BurgersSeries | Miss Bisselbender (voice) | 41 |
| 2010 | The Women of SNLMovie | Various (archive footage) | 40 |
| 2010 | MegamindMovie | Roxanne Ritchi (voice) | 40 |
| 2010 | Date NightMovie | Claire Foster | 40 |
| 2010 | The Marriage RefSeries | Self - Panelist | 40 |
| 2009 | Watch What Happens Live with Andy CohenSeries | Self - Guest | 39 |
| 2009 | The Invention of LyingMovie | Shelley Bailey | 39 |
| 2009 | Late Night with Jimmy FallonSeries | Self - Guest | 39 |
| 2009 | The Jay Leno ShowSeries | Self | 39 |
| 2009 | SpongeBob's Truth or SquareMovie | Self | 39 |
| 2009 | Saturday Night Live: The Best of Amy PoehlerMovie | Various (archive footage) | 39 |
| 2008 | Baby MamaMovie | Kate | 38 |
| 2007 | Phineas and FerbSeries | Annabelle | 37 |
| 2007 | iCarlySeries | Tina Fey | 37 |
| 2007 | The Graham Norton ShowSeries | Self | 37 |
| 2007 | ImpalerMovie | Herself | 37 |
| 2006 | 30 RockSeries | Liz Lemon | 36 |
| 2006 | Man of the YearMovie | Tina Fey | 36 |
| 2006 | Second City: First Family of ComedySeries | Self | 36 |
| 2004 | Mean GirlsMovie | Ms. Norbury | 34 |
| 2003 | The Ellen DeGeneres ShowSeries | Self | 33 |
| 2002 | NBC 75th Anniversary SpecialMovie | Self | 32 |
| 2002 | Live from E!Series | Self | 32 |
| 2002 | Saturday Night Live: The Best of Will FerrellMovie | Self (archive footage) | 32 |
| 1999 | SpongeBob SquarePantsSeries | Herself | 29 |
| 1999 | Saturday Night Live: 25th Anniversary SpecialMovie | Self (uncredited) | 29 |
| 1998 | Upright Citizens BrigadeSeries | — | 28 |
| 1997 | The ViewSeries | Self | 27 |
| 1996 | The Daily ShowSeries | Self | 26 |
| 1996 | E! True Hollywood StorySeries | — | 26 |
| 1993 | Late Show with David LettermanSeries | Self - Top 10 Presenter | 23 |
| 1992 | The Tonight Show with Jay LenoSeries | — | 22 |
| 1989 | The SimpsonsSeries | Ms. Cantwell (voice) | 19 |
| 1988 | LIVE with Kelly and MarkSeries | Self | 18 |
| 1987 | Kids' Choice AwardsSeries | Self | 17 |
| 1981 | Entertainment TonightSeries | Self | 11 |
| 1975 | Saturday Night LiveSeries | Self - Various Characters | 5 |
| 1953 | The OscarsSeries | Self | — |
| 1949 | The Emmy AwardsSeries | Self - Winner & Presenter | — |
| 0 | Second to NoneMovie | — | — |
